+ Phase-I-support-Genotoxicology

Genetic toxicology

A comprehensive range of genetic toxicity services for preclinical assessment and the early screening of candidate compounds. The Genetic Toxicology team works in a purpose-built suite of laboratories and offers a comprehensive selection of genetic toxicity studies.

Introduction

This includes the complete standard range of tests for preclinical safety assessment.

Study Types

  • Bacterial Reverse Mutation Test (Ames Test)
  • Gene Mutation in Mammalian Cells
    • L5178Y TK± Mouse Lymphoma Assay (MLA) 
  • Chromosome aberration
    • Human lymphocytes (HL)
  • In Vitro Micronucleus
    • Human lymphocytes
  • Rodent Micronucleus test
    • Mouse peripheral blood and bone marrow
    • Rat peripheral blood and bone marrow
    • Combination with repeat-dose toxicity
Our News & Events
MDC Connects Webinar 8: Is my Compound Safe?
1 June 2020
Join Sequani for the how to get your molecule in to humans webinar
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Mice in Juvenile Toxicity Testing
26 November 2018
Mice in Juvenile Toxicity Testing
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Biomarker Validation – Mountain, Molehill or Something in Between?
13 June 2018
Biomarker Validation – Mountain, Molehill or Something in Between?
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