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Pathology

 

The Sequani pathology department provides a complete support service for all its toxicology and carcinogenicity studies. Its activities cover necropsy, histopathological processing, microscopic evaluation and pathology interpretation.Pathology

 

We also offered a comprehensive contract service to many international pharmaceutical and chemical companies operating their own animal testing but relying on external professional support to maximise efficiency or to meet scheduling demands.

 

General and Reproduction

Performed by trained technicians in purpose built suites, necropsies are supervised by experienced pathologists in separate facilities for rodents and non-rodents. Data is entered directly onto a dedicated pathology system

Foetal Evaluation

As for General and Reproduction Necropsy, with data captured directly onto an electronic data capture Foetal Pathology System

Histotechnology

A highly efficient laboratory with automated technology can handle over 500,000 tissues a year. Fully trained staff and intrinsic quality systems ensure the work is produced to the highest standard

 

Specialised Procedures

  • frozen sectioning

  • resin embedding

  • specialised embedding

  • photomicrography

  • immunohistochemistry

  • morphometric analysis

  • cell proliferation assays

  • special stains

Microscopic Evaluation

Experienced pathologists, Fellows of the Royal College of Pathology, enter findings directly onto the pathology data system, allowing speedy and flexible reporting according to defined criteria. Enabling full statistical evaluation of pathology findings and tumour incidence.

Sequani pathologists have special expertise in respiratory, endocrine and cardiovascular pathology, carcinogenicity studies, and the pathology of transgenic mice.